Obstructive Sleep Apnoea and Overweight (non-diabetic, not using CPAP machine)

NOW RECRUITING

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Adelaide SA

A research study investigating a new medication to see how it helps people with excess body weight and Obstructive Sleep Apnoea not using CPAP lose weight and improve the sleep apnoea.

Age > 18 years
BMI ≥ 27kg/m2
Non-diabetic
Known moderate to severe OSA (free repeat sleep study during screening)
At least one self reported unsuccessful dietary effort to reduce body weight
No planned or prior surgery for obesity (some exceptions)
No active cancer or history of cancer in last 5 years (some exceptions)
Not taking Ozempic/Mounjaro within 90 days of screening
Weekly self-injection
Sleep Aponea - already diagnosed, unable or unwilling to use CPAP, not intending to start CPAP during study

Outpatient Visit

Screening visit (part 1 and part 2)
Clinic visit every 4 weeks

Payment / Remuneration

Clinic Visits $120
Fasting Visits $25

Information for Practitioners

Screening bloods collected during visit
Sleep study to confirm diagnosis during screening period
Diagnosed moderate-severe Sleep Apnoea (without CPAP, not intenting to start CPAP during the study)
No history of cancers within 5 years of screening
No history of chronic pancreatitis or acute pancreatitis within 180 days of screening
No history of obesity surgery (some allowed >1 yr prior to screening